About Fractyl Health

About Fractyl Health

Addressing the unmet need in the treatment of T2D.

Fractyl Health is an organ editing metabolic therapeutics company focused on pioneering a new approach to the treatment of type 2 diabetes (T2D). Our goal is to transform T2D treatment from chronic blood glucose management to disease-modifying therapies that target the organ-level root causes of metabolic disease.

We have assembled a mission-driven team full of innovators, united in a passion to eradicate type 2 diabetes and to develop breakthrough therapies—the type of therapies we would want for our family members and loved ones with the disease.

Fractyl Health’s purpose is to defend humanity from the metabolic diseases of modernity. Over the past several years, we have gained a deeper understanding of the changes that occur in the gut in response to modern diets. We are singularly focused on developing therapies that are designed to target the root causes of metabolic diseases and delivering our therapies as broadly as possible to as many patients as possible as rapidly as possible.

We believe this approach will be better for patients, better for physicians and better for society. Turning the tide on type 2 diabetes is achievable, but it requires intestinal fortitude. It takes guts.


Our leaders have a wealth of expertise across all stages of therapeutic development and commercialization. Through our accomplished board of directors, investors, and scientific advisors, we have access to some of the most insightful minds in the global scientific and biopharma landscape.

Management Team

Harith Rajagopalan, MD, PhD Open

Harith Rajagopalan, MD, PhD

Co-founder and CEO

Jay Caplan Open

Jay Caplan

Co-founder and President

Lisa Davidson Open

Lisa Davidson

Chief Financial Officer

Juan Carlos Lopez-Talavera, MD, PhD Open

Juan Carlos Lopez-Talavera, MD, PhD

Chief Medical Officer

Jon Fitzgerald Open

Jon Fitzgerald

Vice President of Quality Assurance and Regulatory Affairs

Len Rosberg Open

Len Rosberg

Vice President of Manufacturing

Kelly White, PharmD Open

Kelly White, PharmD

Vice President of Clinical and Medical Affairs

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