At Fractyl, we’re striving to change the lives of patients with metabolic diseases and build the next great medical device company. We’re a tight-knit team that is driven to excel. We’re looking for game-changers. We want people who can solve challenging problems, make a real impact and build something big. Be part of something amazing. Join us.

Our Culturetop

We’re driven to solve real problems and make a deep and enduring impact. We build our business to scale to the size of our mission. We find a way to succeed, as our mission demands it. We are purposeful in our pursuit of excellence. We invest in our people, with an emphasis on individual mastery and team excellence. We believe that achieving our mission is a team sport. We define a clear course of action in an uncertain world, through consensus and commitment. We gather data and apply logic to make the decisions that drive our company’s success. We practice transparency. We continually innovate our business practices for better performance.


We are a team that aims high and strives to make an enduring impact on the lives of patients. By applying the latest scientific knowledge and most cutting edge device technology, our goal is to transform the future of metabolic disease treatment.




Join us and be a part of that transformation.

Opportunities top

Sr. Regulatory Affairs Specialist

Position Summary 
To support its growth and expansion, Fractyl is seeking a Senior Regulatory Affairs Specialist, reporting to the Director of Regulatory Affairs. This role involves participating in the day to day operations of the department as it relates to supporting business needs. This individual will assist in writing and submitting various regulatory submissions and reports, providing guidance to new product development, and help enhance the department’s process and procedures to support the organization’s growth. For full job description, click here.

Clinical Project Manager

Position Summary
Reporting to Fractyl’s President, the Clinical Project Manager provides leadership on the design, initiation and execution of clinical studies to support both product approvals and market adoption of company products. Responsibilities include the initiation and conduct of clinical studies globally with the Fractyl DMR system (Duodenal Mucosal Resurfacing) in the treatment of Type II Diabetes. As a key member of the team, this individual plays a crucial role to establish the Clinical team’s structure in support of Fractyl’s growth and expansion. With hands-on experience, the Clinical Project Manager collaborates with internal and external groups to support the Clinical team’s global initiatives. For full job description, click here.

For more information or to apply, please contact If you don’t see a position that fits your background, we are always happy to receive resumes from great candidates.

We value our agency partnerships, and from time to time solicit their assistance in identifying suitable candidates for our available opportunities. As such, unsolicited agency submissions will not be honored. We promote diversity and are proud to be an Equal Employment Opportunity employer. Fractyl participates in E-Verify.